I don't use CUE.

A quick scan shows several different games affected by a USB / Driver polling race condition (fancy talk for a defect that everyone says belongs to someone else to fix) that's tentatively tied to CUE.

Two courses recommended:

1) Disable / remove CUE
2) Back-rev from 2.x CUE to 1.6 CUE (which reportedly is free of this contention).

Apparently, on 2.x, you can also select Advanced Mode and operate under that profile. The theory goes that Advanced Mode polls much less frequently. To me, much less frequently will only mean it won't crash nearly as often. But - like you - all reports indicate once the race condition hits, the only recovery path is a reboot. So I would opt to go for 'not at all' over 'not as often'.

Best I can do - I have no way to confirm / test / validate any of this information.

Doug